Explore published research on mitochondrial function, cellular energy, (-)-epicatechin, vascular biology, and related metabolic pathways. Browse by specialization below to quickly find the papers most relevant to your interests.
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Obesity and Cardiovascular Risk Improvement Using Cacao By-Products in a Diet-Induced Obesity Murine Model
Hidalgo et al., 2019 · Journal of Medicinal Food
In a diet-induced obesity mouse model, cacao by-products were associated with improvements in obesity-related and cardiovascular risk measures.
A pilot study on clinical pharmacokinetics andpreclinical pharmacodynamics of (+)-epicatechinon cardiometabolic endpoints
Moreno-Ulloa et al., 2018 · Food & Function
This pilot study evaluated the pharmacokinetics, initial safety, and early cardiometabolic effects of (+)-epicatechin in humans and preclinical models, suggesting a favorable early profile.
Effect of cocoa flavanol supplementation for the prevention of cardiovascular disease events: the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial
Sesso et al., 2022 · The American Journal of Clinical Nutrition
The headline result is mixed: null for the primary total-CVD endpoint, but lower CVD death.
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