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    Inhibition of Cancer Cell Metastasis and Invasion

    Study Title: (−)-Epicatechin Inhibits Metastatic-Associated Proliferation, Migration, and Invasion of Murine Breast Cancer Cells In Vitro

    Citation: Pérez-Durán et al., 2023 · Molecules

    What the Study Found: (−)-Epicatechin significantly inhibited proliferation, migration, and invasion of murine breast cancer cells in vitro. It reduced key metastatic markers and altered cell motility pathways. The effects were dose-dependent and linked to modulation of mitochondrial and redox signaling.

    What this means in real life: Metastatic cancer cells depend on dysregulated mitochondrial metabolism to fuel rapid movement and survival. This study shows that (−)-epicatechin can suppress those aggressive behaviors by interfering with energy and redox pathways inside the cells. Supporting mitochondrial health may help create an internal environment less favorable to cancer progression.

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