Study Title: Acute effects of an oral supplement of (-)-epicatechin on postprandial fat and carbohydrate metabolism in normal and overweight subjects
Citation: Gutiérrez-Salmeán et al., 2014 · Food & Function
What the Study Found: A single oral dose of (−)-epicatechin increased postprandial lipid catabolism, shown by a lower respiratory quotient indicating greater fat oxidation. It also lowered postprandial plasma glucose and triglyceride levels, with stronger effects in overweight subjects. These metabolic shifts occurred rapidly after the supplement.
What this means in real life: After meals, mitochondria must quickly switch between burning carbs and fats; when they’re less efficient, blood sugar and fats stay elevated longer. This study shows that (−)-epicatechin can shift the body toward greater fat oxidation right after eating, helping mitochondria handle mixed meals more effectively. Mitochondrial support like this is a simple way to improve everyday metabolic flexibility and energy stability.
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