Sleep and Mitochondria: The Nightly Repair Cycle That Powers Your Day
Ya sabes que dormir es esencial para tu cerebro y tu estado de ánimo, pero ¿sabías que también es fundamental para tus mitocondrias?
Where Energy, Science, and Community Come Together – Mitozz Community
We’re excited to announce that on Lunes, octubre 20th, we officially launched the Mitozz Community, a new digital home for people who want to understand, explore, and share everything about mitochondrial health, cellular energy, and vitality.
How Does Mitochondrial Health Define Your Body? The Real Story of Energy from Within
We often hear that “food gives us energy,” but the truth is a little more complex and a lot more fascinating. The real powerhouses behind your energy are tiny structures inside your cells called mitochondria.
¿Qué es la función mitocondrial y por qué es fundamental para la salud?
Si alguna vez te has sentido sin energía a pesar de dormir bien y comer sano, puede que el problema no sea tu estilo de vida, sino lo que ocurre dentro de tus células. Más concretamente: dentro de tus mitocondrias.
Mitochondrial Biogenesis and Oxidative Stress in Aging
In senile mice, (-)-epicatechin restored markers linked to mitochondrial biogenesis and improved oxidative-stress and aging-related indicators.
Mitochondrial Biogenesis in Muscle Cells via GPER
In C2C12 myotubes, (-)-epicatechin stimulated mitochondrial biogenesis and cell growth, and the study implicated the G-protein–coupled estrogen receptor in that response.
Apelin Receptor Signaling and Biased Agonism
This paper identifies (-)-epicatechin as a biased ligand of the apelin receptor, supporting a receptor-mediated signaling mechanism that may help explain some of its vascular and metabolic effects.
eNOS Activation and Nitric Oxide Signaling Pathways
This study found that (-)-epicatechin activates endothelial nitric oxide synthase and increases nitric oxide signaling in endothelial cells, helping define a plausible endothelial mechanism for vascular benefit.
GPER Receptor and Endothelial Nitric Oxide Production
The authors report that the effects of (-)-epicatechin in endothelial cells involve GPER, adding a specific receptor-linked explanation for observed vascular signaling responses.
Postprandial Fat Oxidation and Epicatechin
This human study assessed short-term metabolic effects of an oral (-)-epicatechin supplement after meals, reporting changes in postprandial fat and carbohydrate handling in normal and overweight participants.
Perilipin Expression and Liver Fat Metabolism in NASH
Using a diet-induced NASH model, this study tracked the time course of perilipin expression and assessed how (-)-epicatechin altered those lipid-droplet–related responses over time.
Endothelial Cell Aging Reversal and Vascular Function
This paper reports that (-)-epicatechin reversed several features of endothelial cell aging and improved vascular function, while also exploring the mechanisms behind those changes.